Every destination here has at least one nonstop from Phoenix Sky Harbor. Flight times are averages for the nonstop.
| Destination | Airport | Nonstop airlines | Flight time | Why go |
|---|---|---|---|---|
| Las Vegas | LAS | Southwest, American, Frontier | 1h 15m | The easiest weekend trip from PHX, with more than 100 nonstops a week. |
| Palm Springs | PSP | American | about 1h 10m | Pools and desert modernism without the Vegas crowds. American is the only nonstop. |
| Albuquerque and Santa Fe | ABQ | Southwest, American | 1h 15m | Fly to Albuquerque, then drive about an hour to Santa Fe. |
| San Diego | SAN | Southwest, American, Alaska, Frontier | 1h 20m | Beach weather most of the year and frequent sales. |
| Long Beach and Orange County | LGB / SNA | Southwest (LGB); American, Southwest, Frontier (SNA) | about 1h 25m | Smaller airports close to the beach towns south of LA. |
| Los Angeles | LAX | American, Southwest, Delta, United, Frontier | 1h 35m | Five LA-area airports have nonstops from PHX. |
| Santa Barbara | SBA | American | about 1h 30m to 2h | Wine country and beaches. Southwest left the route in 2025, so American is the only nonstop. |
| Salt Lake City | SLC | Southwest, Delta, American, Frontier | 1h 45m | Ski weekends in winter, national parks in summer. |
| Denver | DEN | Southwest, United, American, Frontier | 1h 50m | Mountains within an hour of the airport. |
| Monterey | MRY | American | 2h 10m | Carmel, Big Sur and the aquarium, on an American nonstop. |
| Sacramento and Napa | SMF | Southwest, American | 2h 10m | Fly to Sacramento for an hour-long drive to Napa Valley. |
| San Francisco | SFO | United, American, Southwest, Frontier | 2h 15m | Oakland and San Jose are often cheaper alternatives. |
| Los Cabos | SJD | American, Southwest, Frontier | 2h 15m | A beach weekend abroad, on the same clock as Phoenix. Bring a passport. |
| Austin | AUS | Southwest, American | 2h 15m | Live music and food trucks, with plenty of nonstops. |
| Mazatlán | MZT | American | 2h 20m | A quieter Pacific beach town on an American nonstop. Passport required. |
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Las Vegas, San Diego, Los Angeles, Palm Springs, Albuquerque, Denver, Salt Lake City, Santa Barbara, Monterey, Sacramento, San Francisco, Austin, Los Cabos and Mazatlán all have nonstop flights from PHX of about two and a half hours or less.
Among these weekend destinations, Palm Springs, Las Vegas and Albuquerque are the shortest, at around an hour to an hour and a quarter.
Los Cabos: about 2 hours 15 minutes nonstop on American, Southwest or Frontier, and on the same clock as Phoenix all year. You need a passport.
Sources: KAYAK route pages (nonstop airlines and average flight times, last 3 months) and FlightsFrom route data, checked October 2026. Schedules change; confirm before booking.